Evolution and Synthetics

An amazing scientific announcement has recently occurred, we have been able to show that synthetic DNA, XNA, is capable of evolving. This is interesting for several reasons. First, it’s just more evidence of evolution, which should be a rather no brainer at this point. Second, it shows that there are other materials that can function similarly to DNA and RNA. Finally, we can make these structures and they will behave in a similar fashion to DNA and RNA.

If we can create something that evolves under stress, it indicates that evolution is still extremely robust. If this type of material did not evolve, it would have made scientists look at both that material itself and check a few things. First, would we expect this material to evolve. Second, if yes, why doesn’t it evolve. If we are developing a material that is expected to mimic DNA/RNA, it is likely that we would expect it to evolve in a similar fashion. If it doesn’t evolve, then this could have serious consequences. This would not disprove evolution, as DNA/RNA both evolve, it would indicate that either we have the wrong material or that only DNA/RNA can evolve. It would explain why only DNA/RNA have been found on earth and not any other type of xNA material.

Since this material can evolve it leads to interesting questions itself. Did evolution occur  between DNA/RNA and other xNA’s? Did the RNA/DNA combination beat out every other stain of xNA’s? This would be interesting to understand. If RNA/DNA did evolve because it was better suited to Earth’s early environment does that mean that our current environment still suits it best? Could we evolve completely new life forms based on these structures? Only time and more research will allow us to answer these questions. But we do know that these new strains could allow us to develop treatments and other solutions to biological problems.

One way we could answer these questions is if we discover alien life that is based off of non-RNA/DNA combination. This could be in the form of anything from bacteria to full blown organisms. At this point, it is more likely we’ll find a bacteria life form based on another XNA than anything else as they are capable of surviving exposed space transportation, such as on an asteroid.

The fact that we’re able to create XNA is an amazing accomplishment. It indicates that we understand biochemicals required for life to an extent that we are able to create new enzymes that mimic RNA/DNA. We also understand that the most important metric for this experiment is not the fact that we could make a stable XNA, but that it must evolve. A stable or static XNA would not be interesting as it would have no ability to adapt in an environment where there is competition. The ability to change as the conditions change is what separates RNA/DNA from other proteins and enzymes. Only the best combinations are able to change and develop over time.

I’m excited to see how these changes will impact us. I think there are some significant long term implications for this, but at this time I’m not sure what they are. The fact that we’re capable of doing this is an incredible step.

Book Review: Idea Factory, the history of Bell Labs

Yea, I know I’ve just been doing book reviews.

This book was amazing. I had no idea of all the different things that Bell Labs produced from the mid 1920’s until the 1970’s and later. The book focused on the high point of Bell Labs innovation run. It followed the career of several, at the time, famous and prominent scientists that were employed at Bell Labs. Please such as Mervin Kelley (vastly improve the vacuum tube and was a long running director, VP and President of the Labs), William Shockley (inventor of the transistor) Brattian (inventor of a different kind of transistor), Claude Shannon (inventor of the field of Information Science), John Pierce (inventor of passive and active satellite). These there were many others, however, they each had significant impacts on how our modern society works.

The book does an excellent job in explaining some of the basics of how the research was conducted, what work needed to be done to make it work on an experimental level, the method of transferring the invention into innovation or a full product and the goal of each of these inventions. Mervin Kelley was famous for saying that to implement a change in AT&T’s network the new technology must be “better or cheaper or both.” This prevented a great deal of frivolous technologies from being implemented into the telephone network. Additionally, this was required to ensure that AT&T was always able to work towards reducing rates for subscribers as they were a “natural” monopoly.

This was a time when research was done to ensure that the network would be operational for 30 years without malfunction. This required huge investments in quality control and required that additional costs were built into the network for redundancies and protection. In fact Statistical Process Control was invented at Bell Labs to ensure proper quality.

How did all of this work? Well, there were two factors going on here. First, Bell Labs was able to hire the best and brightest to work on interesting problems. Second, the scientists had a continually evolving project that always needed more innovation. These two combined with a freedom to explore allowed the scientists to delve into basic and applied research. In some cases they did not know how or why something would work, but felt that it would improve the quality of the telephone network.

One of the goals of AT&T was to create a coast to coast network with universal service. This required the company to figure out how to address signal decay due to distances over several miles. To address this the company developed the vacuum tube repeater, which significantly increased the distance a voice call could travel. The manufacturing of a tube was extremely difficult and expensive. Bell Labs felt that there had to be a different way to create a repeater. Over the next 20 years they investigated off and on (with a break for WWII) how to make semiconductors work as a repeater. Bell Labs was capable of making this sort of investment because it had a guaranteed revenue stream and a mandate to continually improve the network. These two together allowed the Labs to do work that they otherwise would not have been able to investigate.

This is a very different model for innovation than we currently have in any organization. Universities come close, but they fall short in the fact that the professors are continually required to apply for more money and seek permission from someone to pursue their work. Bell Labs was much more relaxed about this.

This innovation method is also very different than some of the historic events in the US, such as the Manhattan Project or the Moon Landing. Those were single goals which allowed the focus of a great group of minds.There was never any intention of keeping those minds together for the next big project. Bell Labs had the ability to do this.

There are some organizations that should be able to do something like this. The National Labs are one, but there’s no direct business need so even this doesn’t exactly work. An organization like TNO in the Netherlands, which focuses more on practical matters could increase the amount of basic research they conduct in various different areas. TNO is structured differently than the National Labs in the US, because they are expected to work closely with both industry and universities. This gives each of the groups a strong business focus and could serve as a pipeline from basic research into business activities for the companies that work with TNO. However, at this point TNO does not perform these activities.

I give this book a 4.5/5. It was extremely well written, well organized and dealt with some amazing subject matters.

Content and implicit threats

I’m reading “consent of the Networked” right now. The book is about digital rights, privacy, government and the internet. Once i finish I will write a review for the Urban Times. I found out about the book through TechDirt’s book club. One of the major points the author makes about repressive regimes is the activities of pronationalist actors that are not truly part of the government.

These actors are typically regular people and act as hackers, journalists or progovernment rally organizers. They are found in many countries including China, Iran, the former regime of Tunisia and Libya. In a way these groups are a counter weight to “organizations” like Anonymous, dissent groups and the “liberal” media. However, these organizations are unlikely in the US and Europe right?

Well according to the author now. These groups do exist in the US and in some cases are formal business like HBGary. Some of them actually work for the US government and others do with a wink and a nod. These groups help monitor internet users and potential members of groups like Anon. In many cases this extends the impression of continual  observation by the government and other actors, which can lead to self censorship and self selection for activities.

Has this happened to me? You bet it has, but I didn’t really think much of it at the time or how it could really impact me. One of the times happened during a Facebook conversation about Wikileaks, which I was supporting. The person I was discussing doesn’t like me much and thinks I’m “a rube.” He suggested that I should get a job which requires security clearance so I would get an understanding of how things actually work and that I was niave. Of course I disagree with the fact that I’m niave and I view the world in a much more complex manner than his black and white view. However, I had been thinking of applying to a government type position and he told me I should be careful what I say, which he is correct. This then led me to rein in my views and self censor. This had serious implications on how I discussed topics for some time.

The other times are slightly different and after I started blogging. For one my brother is in the Boarder Patrol which gives him clearance and my sister does stuff she can’t talk about. So, to some extent, I don’t want to negatively impact their ability to work either. This does have a moderating affect as well.

The final source was actually my dad writing to me about my post about anonymous and my discussion of using DDoS as potentially a source of public demonstration on the internet. I was not surprised that he suggested I be careful, he did retire as a Major in the Army Reserves. However, when responding I told him I was already being careful with my wording due to self censorship. I already expect that I’m likely to have my material spring up on someone’s radar due to the content I write about. So, I do try to be careful.

In a democracy where these threats should be minimized we have to worry about it. Why should the rest of the world be different or any less oppressive?

Can technology Save us? A wrap up

In my last three posts I’ve asked the question if technology can save us from many of our own problems. I’ve discussed several technologies for each topic, water, energy and food. These technologies are not all of the ones out there by any stretch of the imagination. These are the technologies I’m aware of at this point. I wouldn’t say I’ve done an exhaustive search for technologies either. I hope to have made it obvious that technology alone cannot save us. We need to make a concerted effort to change the status quo and that won’t be easy to do.

We have some major problems adopting new technologies. First, we have incumbents interests that have no desire to see the current energy regime change. We have problems of ownership of technical problems. Why should the US invent new ways to extract water when Mexico is the country that will suffer? How do we know that a given technology is going to be the best, or even good enough for our needs? What happens if all our best efforts turn out to actually make things worse?

These aren’t easy questions to answer. We have to make a choice as a society to decide what constitutes a good investment for research. In one Urban Time article I posit that the EU can over take the US in terms of scientific research in the upcoming decades. This should terrify people. This is what has driven the US economy since the 40’s and to some extent earlier. The shifts in capitalism have driven our company goals toward shorter and shorter returns on investments and less visionary goals. The ability to experiment in companies and use government funds to experiment with deploying new energy systems has floundered.

This should be cause for concern. We’ve seen the result of poorly managed technology in the past few years. Simple things like a software glitch that caused Toyota’s to accelerate out of control, flash crashes on the stock markets from high frequency traders and other complex systems like Fukashima. We don’t always have proper controls designed into our technologies to protect us from it.

Personally, I’m optimistic about the future of technology and what it can do for us. However, there are plenty of Sci-fi authors out there that are very pessimistic. I love reading the dystopian future and post-apocalyptic books as much (or more) than anyone and we need to realize that without requiring proper controls on our technology and production of our material goods these results could happen.

Technology alone cannot save us from ourselves. We may be able to use technology as a tool to fix problems we’ve created, but we have to do the dirty work. Technology doesn’t design and make itself (yet).

Can technology save us: Food production?

In 1768 Thomas Malthus wrote the Principles of Population, which posited that eventually all populations are held in check by disease and famine. This theory argues that any population that grows to sufficient size will outstrip the resources in that the population requires, which will result in famine disease and population crash. While, this is likely true in a Darwinian sense (he used this as to help develop the theory of evolution) it is not true for populations that are able to innovate and provide additional food resources.

Innovation allows the human population to develop new techniques for providing additional food in the same area of space. In some ways this happens through domesticating crops such as corn or bananas and increasing the size of the produce until it hardly looks like the wild version of the produce, which can be seen below for the banana. For a fruit that is roughly the same size an individual will receive a great deal more energy than with the wild fruit.

Source: Wikimedia

Obviously bigger fruits and vegetables aren’t the only product that we’ve seen increase in density of calories. Cattle are being breed to be larger and provide more meat on a single cow. In the extreme case, the Belgian Blue, they are so large they are unable to reproduce without human assistance and are taller than most cattle at the shoulder.

In many cases our cattle, pigs and chickens are being raised in some pretty terrible living conditions. These living conditions cause pollution of our land, cause diseases and can be smelled for hundreds of miles away from the farm. The production of the meat isn’t healthy for the animals nor for the people that live near them. However, for most people it’s out of sight out of mind, or they can’t afford to pay the market for humanely raised animals (grass fed beef or free range chickens).

In the US there’s child hunger, but there is famine in other parts of the world. Part of this is due to poverty, water shortages or powerful people withholding the food that is available. What technologies are out there that may be able to address some of these problems?

One of the most interesting me to me is Lab Grown Meat. This would remove the requirement of using killing animals to provide the meat and proteins we need to survive. Currently, these meats don’t taste all that great and most people would likely be against eating it. However, it could actually lead to a lot of other benefits. For one, if we are able to get cow meat to taste right, that means that we have the muscle and fat ratio correct. This could also allow us to use the same method to rebuild muscle mass for people who have been injured. Other benefits for people with special diets, like vegetarian or vegan, may be able to eat the meats because they aren’t coming from animals.

Labs devoted to growing animal meat would reduce the amount of corn and grains going to cattle and would increase the general supply of these foodstuffs. Additionally, the area required to grow animal meat would be a lot smaller than that to raise a herd of cattle. We won’t be able to replace every source of meat with this, but it is likely that it could replace a lot of it.

Another interesting idea is called the Vertical Farm Project. Instead of a farm taking up huge tracts of land, the farm could be contained in a single structure. It could take the idea of local to the extreme. There could be different floors for each type of crops and the crops could be grown using hydroponics or in a more traditional method if desired. These towers are planned to help power themselves through wind and solar power collectors. The crops would receive both artificial and natural sunlight through large windows and UV lights.

It is also likely that aside from simply providing crops the lower levels could also be used to house a version of grass fed cattle. The number of cows in the herd would have to be very small, but the manure could provide the nutrients some of the crops require. Additionally, since the air would be filtered it would reduce the impact of the smell of the cattle in the surrounding areas. The air circulation equipment could also filter out methane that the cows release and use that as an additional power source by burning it. The idea of a vertical farm like that would essentially ensure that all the material within the farm would be reused and maximize the sustainability of the farm.

At this point these ideas aren’t yet proven to work. It is going to be some time before these technologies are going to be fully workable and deployed to the general public. They could work in both the developed world and the developing. The vertical farm could seriously help the sub Sahara countries in Africa as it is likely that a vertical farm like that would be able to provide crops that normally would not grow outside of the farm. Additionally, the vertical farm could have a water collector on the top and use sun light to convert ocean water into drinkable water through a evaporation and collection.